Inactivation of Pmel Alters Melanosome Shape But Has Only a Subtle Effect on Visible Pigmentation

PMEL is an amyloidogenic protein that appears to be exclusively expressed in pigment cells and forms intralumenal fibrils within early stage melanosomes upon which eumelanins deposit in later stages. PMEL is well conserved among vertebrates, and allelic variants in several species are associated wit...

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Główni autorzy: Hellström, Anders R., Watt, Brenda, Fard, Shahrzad Shirazi, Tenza, Danièle, Mannström, Paula, Narfström, Kristina, Ekesten, Björn, Ito, Shosuke, Wakamatsu, Kazumasa, Larsson, Jimmy, Ulfendahl, Mats, Kullander, Klas, Raposo, Graça, Kerje, Susanne, Hallböök, Finn, Marks, Michael S., Andersson, Leif
Format: Artigo
Język:Inglês
Wydane: Public Library of Science 2011
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174228/
https://ncbi.nlm.nih.gov/pubmed/21949658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002285
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