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Roles of different pools of the mitotic checkpoint complex and the mechanisms of their disassembly
The mitotic (or spindle assembly) checkpoint system prevents premature separation of sister chromatids in mitosis. When the checkpoint is turned on, the mitotic checkpoint complex (MCC) inhibits the ubiquitin ligase anaphase-promoting complex/cyclosome (APC/C). MCC is composed of the checkpoint prot...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3696808/ https://ncbi.nlm.nih.gov/pubmed/23754430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308928110 |
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