The Arrestin-selective Angiotensin AT(1) Receptor Agonist [Sar(1),Ile(4),Ile(8)]-AngII Negatively Regulates Bradykinin B(2) Receptor Signaling via AT(1)-B(2) Receptor Heterodimers

The renin-angiotensin and kallikrein-kinin systems are key regulators of vascular tone and inflammation. Angiotensin II, the principal effector of the renin-angiotensin system, promotes vasoconstriction by activating angiotensin AT(1) receptors. The opposing effects of the kallikrein-kinin system ar...

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Detalhes bibliográficos
Main Authors: Wilson, Parker C., Lee, Mi-Hye, Appleton, Kathryn M., El-Shewy, Hesham M., Morinelli, Thomas A., Peterson, Yuri K., Luttrell, Louis M., Jaffa, Ayad A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696663/
https://ncbi.nlm.nih.gov/pubmed/23661707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.472381
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