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Low-Density Lipoprotein Induced Expression of Connective Tissue Growth Factor via Transactivation of Sphingosine 1-Phosphate Receptors in Mesangial Cells

The pro-fibrotic connective tissue growth factor (CTGF) has been linked to the development and progression of diabetic vascular and renal disease. We recently reported that low-density lipoproteins (LDL) induced expression of CTGF in aortic endothelial cells. However, the molecular mechanisms are no...

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Detalhes bibliográficos
Main Authors: El-Shewy, Hesham M., Sohn, Mimi, Wilson, Parker, Hye Lee, Mi, Hammad, Samar M., Luttrell, Louis M., Jaffa, Ayad A.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355554/
https://ncbi.nlm.nih.gov/pubmed/22422617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1261
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