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Clusters of Branched Aliphatic Side Chains Serve As Cores of Stability in the Native State of the HisF TIM Barrel Protein

Imidazole-3-glycerol phosphate synthase is a heterodimeric allosteric enzyme that catalyzes consecutive reactions in imidazole biosynthesis through its HisF and HisH subunits. The unusually slow unfolding reaction of the isolated HisF TIM barrel domain from the thermophilic bacteria, Thermotoga mari...

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Bibliografische gegevens
Hoofdauteurs: Gangadhara, Basavanapura N., Laine, Jennifer M., Kathuria, Sagar V., Massi, Francesca, Matthews, C. Robert
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696590/
https://ncbi.nlm.nih.gov/pubmed/23333740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.01.002
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