Dependence receptor UNC5D mediates nerve growth factor depletion–induced neuroblastoma regression

Spontaneous regression of neuroblastoma (NB) resembles the developmentally regulated programmed cell death (PCD) of sympathetic neurons. Regressing tumor cells express high levels of the nerve growth factor (NGF) receptors TRKA and p75(NTR) and are dependent on NGF for survival; however, the underly...

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Main Authors: Zhu, Yuyan, Li, Yuanyuan, Haraguchi, Seiki, Yu, Meng, Ohira, Miki, Ozaki, Toshinori, Nakagawa, Atsuko, Ushijima, Toshikazu, Isogai, Eriko, Koseki, Haruhiko, Nakamura, Yohko, Kong, Cuize, Mehlen, Patrick, Arakawa, Hirofumi, Nakagawara, Akira
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Clinical Investigation 2013
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696554/
https://ncbi.nlm.nih.gov/pubmed/23778138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65988
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