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Dependence receptor UNC5D mediates nerve growth factor depletion–induced neuroblastoma regression
Spontaneous regression of neuroblastoma (NB) resembles the developmentally regulated programmed cell death (PCD) of sympathetic neurons. Regressing tumor cells express high levels of the nerve growth factor (NGF) receptors TRKA and p75(NTR) and are dependent on NGF for survival; however, the underly...
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Main Authors: | , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3696554/ https://ncbi.nlm.nih.gov/pubmed/23778138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65988 |
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