Dependence receptor UNC5D mediates nerve growth factor depletion–induced neuroblastoma regression

Spontaneous regression of neuroblastoma (NB) resembles the developmentally regulated programmed cell death (PCD) of sympathetic neurons. Regressing tumor cells express high levels of the nerve growth factor (NGF) receptors TRKA and p75(NTR) and are dependent on NGF for survival; however, the underly...

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Autors principals: Zhu, Yuyan, Li, Yuanyuan, Haraguchi, Seiki, Yu, Meng, Ohira, Miki, Ozaki, Toshinori, Nakagawa, Atsuko, Ushijima, Toshikazu, Isogai, Eriko, Koseki, Haruhiko, Nakamura, Yohko, Kong, Cuize, Mehlen, Patrick, Arakawa, Hirofumi, Nakagawara, Akira
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696554/
https://ncbi.nlm.nih.gov/pubmed/23778138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65988
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