Oncogenic Lmo3 cooperates with Hen2 to induce hydrocephalus in mice

We previously reported that LMO3 and HEN2 act as oncogenes in neuroblastoma development through up-regulating MASH1 transcription by interfering with HES1. To confirm these results in vivo, we generated transgenic mice of these genes. Lmo3 or Hen2 was expressed under the control of Wnt1 promoter, wh...

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Detalhes bibliográficos
Publicado no:Exp Anim
Main Authors: Isogai, Eriko, Okumura, Kazuhiro, Saito, Megumi, Yoshizawa, Yasuhiro, Itoh, Kyoko, Tando, So, Ohira, Miki, Haraguchi, Seiki, Nakagawara, Akira, Fushiki, Shinji, Nagase, Hiroki, Wakabayashi, Yuichi
Formato: Artigo
Idioma:Inglês
Publicado em: Japanese Association for Laboratory Animal Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637378/
https://ncbi.nlm.nih.gov/pubmed/26156403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1538/expanim.15-0026
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