Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus

Recent evidence suggests that enhanced neutrophil extracellular trap (NET) formation activates plasmacytoid dendritic cells and serves as a source of autoantigens in SLE. We propose that aberrant NET formation is also linked to organ damage and to the premature vascular disease characteristic of hum...

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Autors principals: Knight, Jason S., Zhao, Wenpu, Luo, Wei, Subramanian, Venkataraman, O’Dell, Alexander A., Yalavarthi, Srilakshmi, Hodgin, Jeffrey B., Eitzman, Daniel T., Thompson, Paul R., Kaplan, Mariana J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696545/
https://ncbi.nlm.nih.gov/pubmed/23722903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67390
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