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Mechanisms of Siglec-F-Induced Eosinophil Apoptosis: A Role for Caspases but Not for SHP-1, Src Kinases, NADPH Oxidase or Reactive Oxygen

BACKGROUND: Siglec-F and Siglec-8 are functional paralog proapoptotic cell surface receptors expressed on mouse and human eosinophils, respectively. Whereas Siglec-8 mediated death involves caspases and/or reactive oxygen species (ROS) generation and mitochondrial injury, very little is known about...

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Bibliografske podrobnosti
Main Authors: Mao, Hui, Kano, Gen, Hudson, Sherry A., Brummet, Mary, Zimmermann, Nives, Zhu, Zhou, Bochner, Bruce S.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695997/
https://ncbi.nlm.nih.gov/pubmed/23840825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068143
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