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Regulation of Siglec-8-induced intracellular reactive oxygen species production and eosinophil cell death by Src family kinases
RATIONALE: Siglec-8 is a surface receptor predominantly expressed on human eosinophils where its ligation induces reactive oxygen species (ROS) formation and cell death. Since Siglec-8 has intracellular tyrosine-based motifs, we hypothesized that Src family kinases (SFKs) are involved in ROS formati...
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| Pubblicato in: | Immunobiology |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5154890/ https://ncbi.nlm.nih.gov/pubmed/27682013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2016.09.006 |
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