The core promoter region of the tumor necrosis factor alpha gene confers phorbol ester responsiveness to upstream transcriptional activators.

Activators of protein kinase C, such as 12-O-tetradecanoylphorbol 13-acetate (TPA), are known to regulate the expression of many genes, including the tumor necrosis factor alpha (TNF) gene, by affecting the level or activity of upstream transcription factors. To investigate the mechanism whereby TPA...

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Библиографические подробности

Опубликовано в::	Mol Cell Biol
Главные авторы:	Leitman, D C, Mackow, E R, Williams, T, Baxter, J D, West, B L
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Taylor & Francis 1992
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369568/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1545816/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.3.1352-1356.1992
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