The core promoter region of the tumor necrosis factor alpha gene confers phorbol ester responsiveness to upstream transcriptional activators.

Activators of protein kinase C, such as 12-O-tetradecanoylphorbol 13-acetate (TPA), are known to regulate the expression of many genes, including the tumor necrosis factor alpha (TNF) gene, by affecting the level or activity of upstream transcription factors. To investigate the mechanism whereby TPA...

詳細記述

書誌詳細

出版年:	Mol Cell Biol
主要な著者:	Leitman, D C, Mackow, E R, Williams, T, Baxter, J D, West, B L
フォーマット:	Artigo
言語:	Inglês
出版事項:	Taylor & Francis 1992
主題:	Research Article
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369568/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1545816/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.3.1352-1356.1992
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