The core promoter region of the tumor necrosis factor alpha gene confers phorbol ester responsiveness to upstream transcriptional activators.

Activators of protein kinase C, such as 12-O-tetradecanoylphorbol 13-acetate (TPA), are known to regulate the expression of many genes, including the tumor necrosis factor alpha (TNF) gene, by affecting the level or activity of upstream transcription factors. To investigate the mechanism whereby TPA...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Leitman, D C, Mackow, E R, Williams, T, Baxter, J D, West, B L
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369568/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1545816/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.3.1352-1356.1992
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