Single-cell paired-end genome sequencing reveals structural variation per cell cycle

The nature and pace of genome mutation is largely unknown. Because standard methods sequence DNA from populations of cells, the genetic composition of individual cells is lost, de novo mutations in cells are concealed within the bulk signal and per cell cycle mutation rates and mechanisms remain elu...

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Dades bibliogràfiques
Autors principals: Voet, Thierry, Kumar, Parveen, Van Loo, Peter, Cooke, Susanna L., Marshall, John, Lin, Meng-Lay, Zamani Esteki, Masoud, Van der Aa, Niels, Mateiu, Ligia, McBride, David J., Bignell, Graham R., McLaren, Stuart, Teague, Jon, Butler, Adam, Raine, Keiran, Stebbings, Lucy A., Quail, Michael A., D’Hooghe, Thomas, Moreau, Yves, Futreal, P. Andrew, Stratton, Michael R., Vermeesch, Joris R., Campbell, Peter J.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
Matèries:
Genomics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695511/
https://ncbi.nlm.nih.gov/pubmed/23630320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt345
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