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Nonallelic homologous recombination between retrotransposable elements is a driver of de novo unbalanced translocations
Large-scale analysis of balanced chromosomal translocation breakpoints has shown nonhomologous end joining and microhomology-mediated repair to be the main drivers of interchromosomal structural aberrations. Breakpoint sequences of de novo unbalanced translocations have not yet been investigated sys...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3589530/ https://ncbi.nlm.nih.gov/pubmed/23212949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.145631.112 |
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