Nonallelic homologous recombination between retrotransposable elements is a driver of de novo unbalanced translocations

Large-scale analysis of balanced chromosomal translocation breakpoints has shown nonhomologous end joining and microhomology-mediated repair to be the main drivers of interchromosomal structural aberrations. Breakpoint sequences of de novo unbalanced translocations have not yet been investigated sys...

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Bibliographic Details
Main Authors: Robberecht, Caroline, Voet, Thierry, Esteki, Masoud Zamani, Nowakowska, Beata A., Vermeesch, Joris R.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2013
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589530/
https://ncbi.nlm.nih.gov/pubmed/23212949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.145631.112
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