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Effect of mutations in a zinc-binding domain of yeast RNA polymerase C (III) on enzyme function and subunit association.

The conserved amino-terminal region of the largest subunit of yeast RNA polymerase C is capable of binding zinc ions in vitro. By oligonucleotide-directed mutagenesis, we show that the putative zinc-binding motif CX2CX6-12CXGHXGX24-37CX2C, present in the largest subunit of all eukaryotic and archaeb...

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Udgivet i:Mol Cell Biol
Principais autores: Werner, M, Hermann-Le Denmat, S, Treich, I, Sentenac, A, Thuriaux, P
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369540/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1545791/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.3.1087-1095.1992
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