A34.5, a nonessential component of yeast RNA polymerase I, cooperates with subunit A14 and DNA topoisomerase I to produce a functional rRNA synthesis machine.

A34.5, a phosphoprotein copurifying with RNA polymerase I (Pol I), lacks homology to any component of the Pol II or Pol III transcription complexes. Cells devoid of A34.5 hardly affect growth and rRNA synthesis and generate a catalytically active but structurally modified enzyme also lacking subunit...

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Detalhes bibliográficos
Main Authors: Gadal, O, Mariotte-Labarre, S, Chedin, S, Quemeneur, E, Carles, C, Sentenac, A, Thuriaux, P
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC232025/
https://ncbi.nlm.nih.gov/pubmed/9121426
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