A34.5, a nonessential component of yeast RNA polymerase I, cooperates with subunit A14 and DNA topoisomerase I to produce a functional rRNA synthesis machine.

A34.5, a phosphoprotein copurifying with RNA polymerase I (Pol I), lacks homology to any component of the Pol II or Pol III transcription complexes. Cells devoid of A34.5 hardly affect growth and rRNA synthesis and generate a catalytically active but structurally modified enzyme also lacking subunit...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Gadal, O, Mariotte-Labarre, S, Chedin, S, Quemeneur, E, Carles, C, Sentenac, A, Thuriaux, P
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1997
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232025/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9121426/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.4.1787
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