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A34.5, a nonessential component of yeast RNA polymerase I, cooperates with subunit A14 and DNA topoisomerase I to produce a functional rRNA synthesis machine.

A34.5, a phosphoprotein copurifying with RNA polymerase I (Pol I), lacks homology to any component of the Pol II or Pol III transcription complexes. Cells devoid of A34.5 hardly affect growth and rRNA synthesis and generate a catalytically active but structurally modified enzyme also lacking subunit...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Gadal, O, Mariotte-Labarre, S, Chedin, S, Quemeneur, E, Carles, C, Sentenac, A, Thuriaux, P
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1997
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232025/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9121426/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.4.1787
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