A universally conserved region of the largest subunit participates in the active site of RNA polymerase III.

The largest subunits of the three eukaryotic nuclear RNA polymerase present extensive sequence homology with the beta' subunit of the bacterial enzymes over five major co-linear regions. Region d is the most highly conserved and contains a motif, (Y/F)NADFDGD(E/Q)M(N/A), which is invariant in a...

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Main Authors: Dieci, G, Hermann-Le Denmat, S, Lukhtanov, E, Thuriaux, P, Werner, M, Sentenac, A
Formato: Artigo
Idioma:Inglês
Publicado: 1995
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC394451/
https://ncbi.nlm.nih.gov/pubmed/7641695
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