Effect of mutations in a zinc-binding domain of yeast RNA polymerase C (III) on enzyme function and subunit association.

The conserved amino-terminal region of the largest subunit of yeast RNA polymerase C is capable of binding zinc ions in vitro. By oligonucleotide-directed mutagenesis, we show that the putative zinc-binding motif CX2CX6-12CXGHXGX24-37CX2C, present in the largest subunit of all eukaryotic and archaeb...

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Détails bibliographiques

Publié dans:	Mol Cell Biol
Auteurs principaux:	Werner, M, Hermann-Le Denmat, S, Treich, I, Sentenac, A, Thuriaux, P
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1992
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369540/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1545791/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.3.1087-1095.1992
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