Generation of Recombinant Human Parainfluenza Virus Type 1 Vaccine Candidates by Importation of Temperature-Sensitive and Attenuating Mutations from Heterologous Paramyxoviruses

Human parainfluenza virus type 1 (HPIV1) is a significant cause of respiratory tract disease in infants and young children for which a vaccine is needed. In the present study, we sought to attenuate HPIV1 by the importation of one or more known attenuating point mutations from heterologous paramyxov...

Popoln opis

Bibliografske podrobnosti

izdano v:	J Virol
Principais autores:	Newman, Jason T., Riggs, Jeffrey M., Surman, Sonja R., McAuliffe, Josephine M., Mulaikal, Teresa A., Collins, Peter L., Murphy, Brian R., Skiadopoulos, Mario H.
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2004
Teme:	Vaccines and Antiviral Agents
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369514/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14747566/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.4.2017-2028.2004
Oznake:	Označite Brez oznak, prvi označite!