Generation of Recombinant Human Parainfluenza Virus Type 1 Vaccine Candidates by Importation of Temperature-Sensitive and Attenuating Mutations from Heterologous Paramyxoviruses

Human parainfluenza virus type 1 (HPIV1) is a significant cause of respiratory tract disease in infants and young children for which a vaccine is needed. In the present study, we sought to attenuate HPIV1 by the importation of one or more known attenuating point mutations from heterologous paramyxov...

Descrición completa

Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Newman, Jason T., Riggs, Jeffrey M., Surman, Sonja R., McAuliffe, Josephine M., Mulaikal, Teresa A., Collins, Peter L., Murphy, Brian R., Skiadopoulos, Mario H.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2004
Assuntos:	Vaccines and Antiviral Agents
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369514/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14747566/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.4.2017-2028.2004
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!