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Continuous Aging of the Human DNA Methylome Throughout the Human Lifespan

DNA methylation plays an important role in development of disease and the process of aging. In this study we examine DNA methylation at 476,366 sites throughout the genome of white blood cells from a population cohort (N = 421) ranging in age from 14 to 94 years old. Age affects DNA methylation at a...

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書目詳細資料
Main Authors: Johansson, Åsa, Enroth, Stefan, Gyllensten, Ulf
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695075/
https://ncbi.nlm.nih.gov/pubmed/23826282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067378
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