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Strong effects of genetic and lifestyle factors on biomarker variation and use of personalized cutoffs

Ideal biomarkers used for disease diagnosis should display deviating levels in affected individuals only and be robust to factors unrelated to the disease. Here we show the impact of genetic, clinical and lifestyle factors on circulating levels of 92 protein biomarkers for cancer and inflammation, u...

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Bibliografski detalji
Glavni autori: Enroth, Stefan, Johansson, Åsa, Enroth, Sofia Bosdotter, Gyllensten, Ulf
Format: Artigo
Jezik:Inglês
Izdano: Nature Pub. Group 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143927/
https://ncbi.nlm.nih.gov/pubmed/25147954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5684
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