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Strong effects of genetic and lifestyle factors on biomarker variation and use of personalized cutoffs

Ideal biomarkers used for disease diagnosis should display deviating levels in affected individuals only and be robust to factors unrelated to the disease. Here we show the impact of genetic, clinical and lifestyle factors on circulating levels of 92 protein biomarkers for cancer and inflammation, u...

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Detalhes bibliográficos
Main Authors: Enroth, Stefan, Johansson, Åsa, Enroth, Sofia Bosdotter, Gyllensten, Ulf
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143927/
https://ncbi.nlm.nih.gov/pubmed/25147954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5684
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