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Strong effects of genetic and lifestyle factors on biomarker variation and use of personalized cutoffs
Ideal biomarkers used for disease diagnosis should display deviating levels in affected individuals only and be robust to factors unrelated to the disease. Here we show the impact of genetic, clinical and lifestyle factors on circulating levels of 92 protein biomarkers for cancer and inflammation, u...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Pub. Group
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4143927/ https://ncbi.nlm.nih.gov/pubmed/25147954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5684 |
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