Continuous Aging of the Human DNA Methylome Throughout the Human Lifespan

DNA methylation plays an important role in development of disease and the process of aging. In this study we examine DNA methylation at 476,366 sites throughout the genome of white blood cells from a population cohort (N = 421) ranging in age from 14 to 94 years old. Age affects DNA methylation at a...

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Detalhes bibliográficos
Main Authors: Johansson, Åsa, Enroth, Stefan, Gyllensten, Ulf
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695075/
https://ncbi.nlm.nih.gov/pubmed/23826282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067378
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https://ncbi.nlm.nih.gov/pmc/articles/PMC3695075/
https://ncbi.nlm.nih.gov/pubmed/23826282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067378