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Continuous Aging of the Human DNA Methylome Throughout the Human Lifespan.

DNA methylation plays an important role in development of disease and the process of aging. In this study we examine DNA methylation at 476,366 sites throughout the genome of white blood cells from a population cohort (N = 421) ranging in age from 14 to 94 years old. Age affects DNA methylation at a...

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Main Authors: Asa Johansson, Stefan Enroth, Ulf Gyllensten
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC3695075?pdf=render
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