DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape

Transposable element (TE) derived sequences comprise half of our genome and DNA methylome, and are presumed densely methylated and inactive. Examination of the genome-wide DNA methylation status within 928 TE subfamilies in human embryonic and adult tissues revealed unexpected tissue-specific and su...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Xie, Mingchao, Hong, Chibo, Zhang, Bo, Lowdon, Rebecca, Xing, Xiaoyun, Li, Daofeng, Zhou, Xin, Lee, Hyung Joo, Maire, Cecile L., Ligon, Keith L., Gascard, Philippe, Sigaroudinia, Mahvash, Tlsty, Thea D., Kadlecek, Theresa, Weiss, Arthur, O’Geen, Henriette, Farnham, Peggy J., Madden, Pamela A.F., Mungall, Andrew J., Tam, Angela, Kamoh, Baljit, Cho, Stephanie, Moore, Richard, Hirst, Martin, Marra, Marco A., Costello, Joseph F., Wang, Ting
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695047/
https://ncbi.nlm.nih.gov/pubmed/23708189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2649
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk