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Carcinoma-associated fibroblasts: orchestrating the composition of malignancy

The tumor stroma is no longer seen solely as physical support for mutated epithelial cells but as an important modulator and even a driver of tumorigenicity. Within the tumor stromal milieu, heterogeneous populations of fibroblast-like cells, collectively termed carcinoma-associated fibroblasts (CAF...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Main Authors: Gascard, Philippe, Tlsty, Thea D.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863733/
https://ncbi.nlm.nih.gov/pubmed/27151975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.279737.116
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