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SOX2, OCT3/4 and NANOG Expression and Cellular Plasticity in Rare Human Somatic Cells Requires CD73

Endogenous Plastic Somatic (ePS) cells isolated from adult human tissues exhibit extensive lineage plasticity in vitro and in vivo. Here we visualize these rare ePS cells in a latent state, i.e. lacking SOX2, OCT3/4 and NANOG (SON) expression, in non-diseased breast specimens through immunohistochem...

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Detalhes bibliográficos
Publicado no:Cell Signal
Main Authors: Pan, Deng, Roy, Somdutta, Gascard, Philippe, Zhao, Jianxin, Chen-Tanyolac, Chira, Tlsty, Thea D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5107210/
https://ncbi.nlm.nih.gov/pubmed/27705752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2016.09.008
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