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Tpt1 Activates Transcription of oct4 and nanog in Transplanted Somatic Nuclei

Nuclear transfer to eggs or oocytes provides a potential route for cell-replacement therapies [1] because oocytes directly reprogram transplanted mammalian somatic-cell nuclei such that they have an embryo-like pattern of gene expression. This includes a large increase in the mRNA level of the stem-...

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Detalles Bibliográficos
Autores principales: Koziol, Magdalena J., Garrett, Nigel, Gurdon, J.B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cell Press 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1871616/
https://ncbi.nlm.nih.gov/pubmed/17442571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2007.03.062
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