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Transcriptional Reprogramming and Chromatin Remodeling Accompanies Oct4 and Nanog Silencing in Mouse Trophoblast Lineage

In mouse blastocysts, CDX2 plays a key role in silencing Oct4 and Nanog expression in the trophectoderm (TE) lineage. However, the underlying transcriptional and chromatin-based changes that are associated with CDX2-mediated repression are poorly understood. To address this, a Cdx2-inducible mouse e...

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Autors principals: Carey, Timothy S., Choi, Inchul, Wilson, Catherine A., Floer, Monique, Knott, Jason G.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904517/
https://ncbi.nlm.nih.gov/pubmed/24059348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2013.0328
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