Global Identification of EVI1 Target Genes in Acute Myeloid Leukemia

The ecotropic virus integration site 1 (EVI1) transcription factor is associated with human myeloid malignancy of poor prognosis and is overexpressed in 8–10% of adult AML and strikingly up to 27% of pediatric MLL-rearranged leukemias. For the first time, we report comprehensive genomewide EVI1 bind...

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Main Authors: Glass, Carolyn, Wuertzer, Charles, Cui, Xiaohui, Bi, Yingtao, Davuluri, Ramana, Xiao, Ying-Yi, Wilson, Michael, Owens, Kristina, Zhang, Yi, Perkins, Archibald
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694976/
https://ncbi.nlm.nih.gov/pubmed/23826213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067134
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