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MARVELD1 Inhibits Nonsense-Mediated RNA Decay by Repressing Serine Phosphorylation of UPF1

We have observed low expression levels of MARVELD1, a novel tumor repressor, in multiple tumors; however, its function in normal cells has not been explored. We recently reported that MARVELD1 interacts with importin β1, which plays an important role in nonsense-mediated RNA decay(NMD). Here, we dem...

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Detalhes bibliográficos
Main Authors: Hu, Jianran, Li, Yu, Li, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694864/
https://ncbi.nlm.nih.gov/pubmed/23826386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068291
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