Pancreatic beta-cell-type-specific transcription of the insulin gene is mediated by basic helix-loop-helix DNA-binding proteins.

Lignende værker

• Identification of a pancreatic beta-cell insulin gene transcription factor that binds to and appears to activate cell-type-specific expression: its possible relationship to other cellular factors that bind to a common insulin gene sequence.
  af: Whelan, J, et al.
  Udgivet: (1990)
• p300 Mediates Transcriptional Stimulation by the Basic Helix-Loop-Helix Activators of the Insulin Gene
  af: Qiu, Yi, et al.
  Udgivet: (1998)
• Intrinsic DNA binding properties demonstrated for lineage-specifying basic helix-loop-helix transcription factors
  af: Casey, Bradford H., et al.
  Udgivet: (2018)
• Distribution and characterization of helix-loop-helix enhancer-binding proteins from pancreatic beta cells and lymphocytes.
  af: Aronheim, A, et al.
  Udgivet: (1991)
• A critical role for the loop region of the basic helix–loop–helix/leucine zipper protein Mlx in DNA binding and glucose-regulated transcription
  af: Ma, Lin, et al.
  Udgivet: (2007)