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Isolation and characterization of a novel transcription factor that binds to and activates insulin control element-mediated expression.

Pancreatic beta-cell-type-specific transcription of the insulin gene is principally regulated by a single cis-acting DNA sequence element, termed the insulin control element (ICE), which is found within the 5'-flanking region of the gene. The ICE activator is a heteromeric complex composed of a...

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Detalles Bibliográficos
Main Authors: Robinson, G L, Cordle, S R, Henderson, E, Weil, P A, Teitelman, G, Stein, R
Formato: Artigo
Idioma:Inglês
Publicado: 1994
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC359201/
https://ncbi.nlm.nih.gov/pubmed/7935390
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