Isolation and characterization of a novel transcription factor that binds to and activates insulin control element-mediated expression.

Pancreatic beta-cell-type-specific transcription of the insulin gene is principally regulated by a single cis-acting DNA sequence element, termed the insulin control element (ICE), which is found within the 5'-flanking region of the gene. The ICE activator is a heteromeric complex composed of an isl...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Robinson, G L, Cordle, S R, Henderson, E, Weil, P A, Teitelman, G, Stein, R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359201/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7935390/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.10.6704-6714.1994
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