Pancreatic beta-cell-type-specific transcription of the insulin gene is mediated by basic helix-loop-helix DNA-binding proteins.

The pancreatic beta-cell-specific expression of the insulin gene is mediated, at least in part, by the interaction of unique trans-acting beta-cell factors with a cis-acting DNA element found within the insulin enhancer (5'-GC CATCTG-3'; referred to as the insulin control element [ICE]) present in t...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Cordle, S R, Henderson, E, Masuoka, H, Weil, P A, Stein, R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369485/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1996119/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.3.1734-1738.1991
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