Cargando...

Saccharomyces cerevisiae DNA Ligase IV Supports Imprecise End Joining Independently of Its Catalytic Activity

DNA ligase IV (Dnl4 in budding yeast) is a specialized ligase used in non-homologous end joining (NHEJ) of DNA double-strand breaks (DSBs). Although point and truncation mutations arise in the human ligase IV syndrome, the roles of Dnl4 in DSB repair have mainly been examined using gene deletions. H...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Chiruvella, Kishore K., Liang, Zhuobin, Birkeland, Shanda R., Basrur, Venkatesha, Wilson, Thomas E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694833/
https://ncbi.nlm.nih.gov/pubmed/23825968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003599
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!