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Galectin-3– and phospho-caveolin-1–dependent outside-in integrin signaling mediates the EGF motogenic response in mammary cancer cells

In murine mammary epithelial cancer cells, galectin-3 binding to β1,6-acetylglucosaminyltransferase V (Mgat5)–modified N-glycans restricts epidermal growth factor (EGF) receptor mobility in the plasma membrane and acts synergistically with phospho-caveolin-1 to promote integrin-dependent matrix remo...

詳細記述

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書誌詳細
主要な著者: Boscher, Cecile, Nabi, Ivan R.
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Cell Biology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694797/
https://ncbi.nlm.nih.gov/pubmed/23657817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-02-0095
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