Galectin-3 Protein Regulates Mobility of N-cadherin and GM1 Ganglioside at Cell-Cell Junctions of Mammary Carcinoma Cells

Galectin-3 binding to cell surface glycoproteins, including branched N-glycans generated by N-acetylglucosaminyltransferase V (Mgat5) activity, forms a multivalent, heterogeneous, and dynamic lattice. This lattice has been shown to regulate integrin and receptor tyrosine kinase signaling promoting t...

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Autores principales: Boscher, Cécile, Zheng, Yu Zi, Lakshminarayan, Ramya, Johannes, Ludger, Dennis, James W., Foster, Leonard J., Nabi, Ivan R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Glycobiology and Extracellular Matrices
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463368/
https://ncbi.nlm.nih.gov/pubmed/22846995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.353334
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