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Phenotypic Conversions of “Protoplasmic” to “Reactive” Astrocytes in Alexander Disease

Alexander Disease (AxD) is a primary disorder of astrocytes, caused by heterozygous mutations in GFAP, which encodes the major astrocyte intermediate filament protein, glial fibrillary acidic protein (GFAP). Astrocytes in AxD display hypertrophy, massive increases in GFAP, and the accumulation of Ro...

詳細記述

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書誌詳細
主要な著者: Sosunov, Alexander A., Guilfoyle, Eileen, Wu, Xiaoping, McKhann, Guy M., Goldman, James E.
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694721/
https://ncbi.nlm.nih.gov/pubmed/23616550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4506-12.2013
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