Genetic variants in the region of the C1q genes are associated with rheumatoid arthritis

Rodent models for arthritis implicate a role for complement in disease development and progression. In humans, complement deposition has been observed in inflamed synovia of rheumatoid arthritis (RA) patients. In this study we analysed whether genetic variants of complement component C1q predispose...

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Detalhes bibliográficos
Main Authors: Trouw, L A, Daha, N, Kurreeman, F A S, Böhringer, S, Goulielmos, G N, Westra, H J, Zhernakova, A, Franke, L, Stahl, E A, Levarht, E W N, Stoeken-Rijsbergen, G, Verduijn, W, Roos, A, Li, Y, Houwing-Duistermaat, J J, Huizinga, T W J, Toes, R E M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Translational Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694537/
https://ncbi.nlm.nih.gov/pubmed/23607884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12097
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