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The fine specificity of IgM anti-citrullinated protein antibodies (ACPA) is different from that of IgG ACPA

INTRODUCTION: The antigen recognition pattern of immunoglobulin M (IgM) could, when directed against protein antigens, provide an indication of the antigenic moieties triggering new B cells. The half-life of IgM is short and memory B cells against T-cell-dependent protein antigens typically produce...

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Main Authors: Suwannalai, Parawee, Willemze, Annemiek, van Toorn, Linda, Stoeken-Rijsbergen, Gerrie, Levarht, Nivine, Drijfhout, Jan Wouter, J Huizinga, Tom W, M Toes, Rene E, Trouw, Leendert A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334645/
https://ncbi.nlm.nih.gov/pubmed/22129077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3524
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