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A dominant negative mutation suppresses the function of normal epidermal growth factor receptors by heterodimerization.

Recent studies provide evidence that defective receptors can function as a dominant negative mutation suppressing the action of wild-type receptors. This causes various diminished responses in cell culture and developmental disorders in murine embryogenesis. Here, we describe a model system and a po...

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Detalhes bibliográficos
Main Authors: Kashles, O, Yarden, Y, Fischer, R, Ullrich, A, Schlessinger, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC369423/
https://ncbi.nlm.nih.gov/pubmed/1705006
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