Monoclonal antibodies against receptor for epidermal growth factor induce early and delayed effects of epidermal growth factor.

Mice were immunized with human epidermoid carcinoma cells (A-431 cell line) that possess an unusually high number of membrane receptors for epidermal growth factor (EGF). Spleen cells from these mice were fused with NSI cells, a nonsecreting murine myeloma. The immunoglobulins secreted by the obtain...

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Bibliografiska uppgifter
Huvudupphovsmän: Schreiber, A B, Lax, I, Yarden, Y, Eshhar, Z, Schlessinger, J
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1981
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC349303/
https://ncbi.nlm.nih.gov/pubmed/6278478
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