The Human Immunodeficiency Virus Type 1 Ribosomal Frameshifting Site Is an Invariant Sequence Determinant and an Important Target for Antiviral Therapy

Human immunodeficiency virus type 1 (HIV-1) utilizes a distinctive form of gene regulation as part of its life cycle, termed programmed −1 ribosomal frameshifting, to produce the required ratio of the Gag and Gag-Pol polyproteins. We carried out a sequence comparison of 1,000 HIV-1 sequences at the...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Biswas, Preetha, Jiang, Xi, Pacchia, Annmarie L., Dougherty, Joseph P., Peltz, Stuart W.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2004
Fag:	Replication
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369415/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14747573/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.4.2082-2087.2004
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