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N-Terminal Extension of Human Immunodeficiency Virus Capsid Protein Converts the In Vitro Assembly Phenotype from Tubular to Spherical Particles

Expression of retroviral Gag polyproteins is sufficient for morphogenesis of virus-like particles with a spherical immature protein shell. Proteolytic cleavage of Gag into the matrix (MA), capsid (CA), nucleocapsid (NC), and p6 domains (in the case of human immunodeficiency virus [HIV]) leads to con...

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Bibliografische gegevens
Hoofdauteurs: Gross, Ingolf, Hohenberg, Heinz, Huckhagel, Carola, Kräusslich, Hans-Georg
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 1998
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC110021/
https://ncbi.nlm.nih.gov/pubmed/9573245
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